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Gastroenterology
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#1Yan-Yi Jiang (NUS: National University of Singapore)H-Index: 18
#2Yuan Jiang (NUS: National University of Singapore)
Last. Jian-Jun Xie (STU: Shantou University)H-Index: 15
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Abstract: Background & Aims We investigated the transcriptome of esophageal squamous cell carcinoma (ESCC) cells, activity of gene regulatory (enhancer and promoter regions), and the effects of blocking epigenetic regulatory proteins. Methods We performed chromatin immunoprecipitation sequencing with antibodies against H3K4me1, H3K4me3, and H3K27ac and an assay for transposase accessible chromatin to map the enhancer regions and accessible chromatin in 8 ESCC cell lines. We used the CRC_Mapper a...
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#1D. Terlouw (LEI: Leiden University)
#2Manon Suerink (LEI: Leiden University)H-Index: 6
Last. Hans Morreau (LEI: Leiden University)H-Index: 47
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#1Saam Dilmaghani (Mayo Clinic)
#2Seth Sweetser (Mayo Clinic)H-Index: 16
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#1M. Phillip Fejleh (UCLA: University of California, Los Angeles)H-Index: 1
#2Sung-Eun Yang (UCLA: University of California, Los Angeles)H-Index: 6
Last. Stephen Kim (UCLA: University of California, Los Angeles)H-Index: 10
view all 3 authors...
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#1Michael M. Skaret (NMCSD: Naval Medical Center San Diego)
#2Diego A. Vicente (NMCSD: Naval Medical Center San Diego)
Last. Adam Deising (NMCSD: Naval Medical Center San Diego)
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#1Tao Zuo (CUHK: The Chinese University of Hong Kong)H-Index: 15
#2Hui Zhan (CUHK: The Chinese University of Hong Kong)H-Index: 1
Last. Francis K.L. Chan (CUHK: The Chinese University of Hong Kong)H-Index: 84
view all 12 authors...
Abstract Backgroud & Aims SARS-CoV-2 infects intestinal cells, and might affect the intestinal microbiota. We investigated changes in the fecal fungal microbiomes (mycobiome) of patients with SARS-CoV-2 infection during hospitalization and upon recovery. Methods We performed deep shotgun metagenomic sequencing analysis of fecal samples from 30 patients with COVID-19 in Hong Kong, from February 5 through May 12, 2020. Fecal samples were collected 2 to 3 times per week from time of hospitalization...
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#1Reto Bertolini (Kantonsspital St. Gallen)H-Index: 1
#2Peter K. Bode (UZH: University of Zurich)H-Index: 11
Last. Mikael Sawatzki (Kantonsspital St. Gallen)H-Index: 3
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#1Rebecca L. Morgan (McMaster University)H-Index: 17
#2Geoffrey A. Preidis (BCM: Baylor College of Medicine)H-Index: 18
Last. Dena Zeraatkar (McMaster University)H-Index: 9
view all 10 authors...
Abstract Background and aims We aimed to compare the effectiveness of single- vs multiple-strain probiotics in a network meta-analysis of randomized trials. Methods We searched MEDLINE, EMBASE, Science Citation Index Expanded, CINAHL, Scopus, Cochrane CENTRAL, BIOSIS Previews, and Google Scholar through January 1, 2019 for studies of single-strain and multi-strain probiotic formulations on outcomes of preterm, low-birthweight neonates. We used a frequentist approach for network meta-analysis and...
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#1Deepa R. Jamwal (UA: University of Arizona)H-Index: 2
#2Daniel Laubitz (UA: University of Arizona)H-Index: 17
Last. Prashanth Setty (UA: University of Arizona)
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Abstract: Background & Aims Intestinal epithelial cells (IECs) provide a barrier that separates the mucosal immune system from the luminal microbiota. IECs constitutively express low levels of major histocompatibility complex (MHC) class II proteins, which are upregulated upon exposure interferon gamma. We investigated the effects of deleting MHCII proteins specifically in mice with infectious, dextran sodium sulfate (DSS)-, and T cell-induced colitis. Methods We disrupted the histocompatibility...
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#1Shazia M. Siddique (UPenn: University of Pennsylvania)H-Index: 5
#2Shahnaz Sultan (UMN: University of Minnesota)H-Index: 9
Last. Hashem B. El-Serag (BCM: Baylor College of Medicine)H-Index: 106
view all 8 authors...
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Endocrinology
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