Functional and structural connectivity of the amygdala in obsessive-compulsive disorder

The amygdala is known to be involved in anxiety processing, but its role in the psychopathology of obsessive-compulsive disorder (OCD) is still unclear. In this MRI study we investigated potential alterations in structural and functional connectivity of the amygdala in 42 adult patients with OCD and 37 healthy subjects. Psychophysiological interaction analysis was used to explore amygdala functional connectivity during a negative affective task....