Original paper

Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells

Volume: 113, Issue: 48, Pages: 13809 - 13814
Published: Nov 14, 2016
Abstract
Rereplication generates double-strand breaks (DSBs) at sites of fork collisions and causes genomic damage, including repeat instability and chromosomal aberrations. However, the primary mechanism used to repair rereplication DSBs varies across different experimental systems. In Drosophila follicle cells, developmentally regulated rereplication is used to amplify six genomic regions, two of which contain genes encoding eggshell proteins. We have...
Paper Details
Title
Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells
Published Date
Nov 14, 2016
Volume
113
Issue
48
Pages
13809 - 13814
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