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Proceedings of the National Academy of Sciences of the United States of America
IF
9.58
Papers
140248
Papers 140515
1 page of 14.1k pages (141k results)
Newest
Ellen Peters51
Estimated H-index: 51
(OSU: Ohio State University),
Mary Kate Tompkins5
Estimated H-index: 5
(OSU: Ohio State University)
+ 3 AuthorsAlexa Meara3
Estimated H-index: 3
(The Ohio State University Wexner Medical Center)
People often laugh about being “no good at math.” Unrecognized, however, is that about one-third of American adults are likely too innumerate to operate effectively in financial and health environments. Two numeric competencies conceivably matter—objective numeracy (ability to “run the numbers” correctly; like literacy but with numbers) and numeric self-efficacy (confidence that provides engagement and persistence in numeric tasks). We reasoned, however, that attaining objective numeracy’s benef...
Justine Sitz1
Estimated H-index: 1
(Laval University),
Sophie Blanchet8
Estimated H-index: 8
(Laval University)
+ 10 AuthorsBrandon C. Smith (UNC: University of North Carolina at Chapel Hill)
High-risk human papillomaviruses (HR-HPVs) promote cervical cancer as well as a subset of anogenital and head and neck cancers. Due to their limited coding capacity, HPVs hijack the host cell’s DNA replication and repair machineries to replicate their own genomes. How this host–pathogen interaction contributes to genomic instability is unknown. Here, we report that HPV-infected cancer cells express high levels of RNF168, an E3 ubiquitin ligase that is critical for proper DNA repair following DNA...
Judhajeet Ray3
Estimated H-index: 3
(Cornell University),
Paul R. Munn1
Estimated H-index: 1
(Cornell University)
+ 4 AuthorsJohn T. Lis85
Estimated H-index: 85
(Cornell University)
Heat shock (HS) initiates rapid, extensive, and evolutionarily conserved changes in transcription that are accompanied by chromatin decondensation and nucleosome loss at HS loci. Here we have employed in situ Hi-C to determine how heat stress affects long-range chromatin conformation in human and Drosophila cells. We found that compartments and topologically associating domains (TADs) remain unchanged by an acute HS. Knockdown of Heat Shock Factor 1 (HSF1), the master transcriptional regulator o...
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