Original paper
Inflammation drives renal scarring in experimental pyelonephritis
Abstract
Acquired renal scarring occurs in a subset of patients following febrile urinary tract infections and is associated with hypertension, proteinuria, and chronic kidney disease. Limited knowledge of histopathology, immune cell recruitment, and gene expression changes during pyelonephritis restricts the development of therapies to limit renal scarring. Here, we address this knowledge gap using immunocompetent mice with vesicoureteral reflux....
Paper Details
Title
Inflammation drives renal scarring in experimental pyelonephritis
Published Date
Jan 1, 2017
Journal
Volume
312
Issue
1
Pages
F43 - F53
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Notes
History