Review paper

Beyond the therapeutic shackles of the monoamines: New mechanisms in bipolar disorder biology

Volume: 72, Pages: 73 - 86
Published: Jan 1, 2017
Abstract
Multiple novel biological mechanisms putatively involved in the etiology of bipolar disorders are being explored. These include oxidative stress, altered glutamatergic neurotransmission, mitochondrial dysfunction, inflammation, cell signaling, apoptosis and impaired neurogenesis. Important clinical translational potential exists for such mechanisms to help underpin development of novel therapeutics – much needed given limitations of current...
Paper Details
Title
Beyond the therapeutic shackles of the monoamines: New mechanisms in bipolar disorder biology
Published Date
Jan 1, 2017
Volume
72
Pages
73 - 86
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