Antibacterial Activity Of Fresh Juices Of Allium Cepa And Zingiber Officinale Against Multidrug Resistant Bacteria

G. O. Adeshina1
Estimated H-index: 1
S. Jibo1
Estimated H-index: 1
V. E. Agu And J. O. Ehinmidu1
Estimated H-index: 1
Antibiotic resistant bacteria are one of the major problems challenging the health care system in general. The antibacterial activity of fresh red and white Allium cepa (Onion) and Zingiber officinale (Ginger) juices against multidrug resistant bacteria viz: Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and Salmonella typhi isolated from salad was investigated using agar well diffusion and agar dilution methods. All the bacteria except Staphylococcus aureus were susceptible to the fresh red and white onion juices with the diameter of zones of inhibition ranging from 15mm – 35mm while the test bacteria isolates were not sensitive to the fresh ginger juice. The Minimum Inhibitory Concentration (M. I. C.) and the Minimum Bactericidal Concentration (M. B. C) values of the fresh onion juices against the test bacteria were low ranging from 3.125%/v – 25.0% /v. This study indicates that the fresh juices of Allium cepa possess significant antibacterial potency against multidrug resistant bacteria. G. O. ADESHINA Department of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria, Nigeria.
  • References (6)
  • Citations (16)
📖 Papers frequently viewed together
1 Citations
76 Citations
1 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
#1Emily A. Wilson (CU: University of Colorado Boulder)H-Index: 1
#2Barbara Demmig-Adams (CU: University of Colorado Boulder)H-Index: 59
Purpose – The purpose of this paper is to provide a comprehensive overview of multiple functions and their underlying mechanisms for two common spices, garlic and onion, containing organosulphur compounds.Design/methodology/approach – Literature review of chemistry, physiology, molecular biology, clinical studies.Findings – Both garlic and onions exert their effects on human health via multiple different functions, including antioxidant, anti‐inflammatory, and antibacterial properties. The organ...
58 CitationsSource
#1K. Nemeth (PAN: Polish Academy of Sciences)H-Index: 1
#2M. K. Piskula (PAN: Polish Academy of Sciences)H-Index: 1
The question as to how far the development of chronic diseases in humans depends on diet still remains open. Simultaneously, epidemiological studies suggest the consumption of a flavonoids rich diet might decrease the risk of degenerative changes and certain diseases. The intake of this group of compounds as to quality and quantity depends on dietary habits and a widespread presence of quercetin in the diet makes this compound one of the key factors. Onion, one of the richest and most common que...
76 CitationsSource
24 Citations
#1V. Ani (CSIR-CFTRI: Central Food Technological Research Institute)H-Index: 2
#2Mandyam C. Varadaraj (CSIR-CFTRI: Central Food Technological Research Institute)H-Index: 7
Last. K. Akhilender Naidu (CSIR-CFTRI: Central Food Technological Research Institute)H-Index: 16
view all 3 authors...
Cumin is one of the commonly used spices in food preparations. It is also used in traditional ayurvedic medicine as a stimulant, carminative and astringent. Earlier we have reported that bitter cumin (Cuminum nigrum L.) possess the most potent antioxidant activity among cumin varieties—cumin, black cumin and bitter cumin. In this study, we have further characterized the polyphenolic compounds of bitter cumin and also their antioxidant and antibacterial activity using different model systems. The...
88 CitationsSource
#1Andrzej B. Hendrich (Wrocław Medical University)H-Index: 15
Flavonoids are found ubiquitously in higher plants and constitute an important component of the majority of peoples' daily diets. The biological activities of flavonoids cover a very broad spectrum, from anticancer and antibacterial activities through to inhibition of bone resorption. In the present paper, the interactions between flavonoids and lipid bilayers as well as biological membranes and their components are reviewed, with special emphasis on the structure-activity relationships and mech...
139 CitationsSource
Abstract Onion and garlic contain many sulfur containing active principles mainly in the form of cysteine derivatives, viz. S-alkyl cysteine sulfoxides which decompose into a variety of thiosulfinates and polysulfides by the action of an enzyme allinase on extraction. Decomposed products are volatile and present in the oils of onion and garlic. They possess antidiabetic, antibiotic, hypocholesterolaemic, fibrinolytic and various other biological actions. In addition to free sulfoxides in alliums...
218 Citations
Cited By16
#1Dushyant Sharma (Maharshi Dayanand University)H-Index: 3
#2Reena Rani (Maharshi Dayanand University)H-Index: 2
Last. Jaya Parkash Yadav (Maharshi Dayanand University)H-Index: 18
view all 5 authors...
Abstract Pathogenic microorganisms have emerged as Multi Drug Resistant (MDR) and in the past years the infectious diseases caused by MDR have increased dramatically. The aim of this study is to investigate the antibacterial potential of Allium cepa and isolated quercetin along with molecular docking with the proteins responsible for drug resistance. Methanol extract of A. cepa was prepared and the quercetin was isolated by collecting the fraction using HPLC. Antibacterial activity against three...
#1Joaheer D. Teshika (UoM: University of Mauritius)H-Index: 1
#2Aumeeruddy M. Zakariyyah (UoM: University of Mauritius)H-Index: 1
Last. Mahomoodally Mohamad Fawzi (UoM: University of Mauritius)H-Index: 1
view all 7 authors...
AbstractOnion, (Allium cepa L.), is one of the most consumed and grown vegetable crops in the world. Onion bulb, with its characteristic flavor, is the third most essential horticultural spice with a substantial commercial value. Apart from its culinary virtues, A. cepa is also used traditionally for its medicinal virtues in a plethora of indigenous cultures. Several publications have been produced in an endeavor to validate such traditional claims. Nonetheless, there is still a dearth of up-to-...
6 CitationsSource
Whey is the largest and highly nutritious by-product obtained during manufacturing of cheese, chhanna and paneer. For nutritive and economic utilization of whey, technology for carbonated lemon beverage was developed by optimizing the rate of addition of lemon juice i.e., 4.0%, 4.5%, 5.0% and 5.5% and sugar levels i.e., 8%, 10% and 12%. The average total solids (%), protein (%), ash (%), ascorbic acid (mg/100 g) and total soluble solids (%) content in whey beverage varied from 14.47 to 18.45, 0....
#1Anwesa Bag (ISI: Indian Statistical Institute)H-Index: 10
#2Rabi Ranjan Chattopadhyay (ISI: Indian Statistical Institute)H-Index: 12
The present study was carried out to evaluate the possible synergistic interactions on antibacterial and antioxidant efficacy of essential oils of some selected spices and herbs [bay leaf, black pepper, coriander (seed and leaf), cumin, garlic, ginger, mustard, onion and turmeric] in combination. Antibacterial combination effect was evaluated against six important food-borne bacteria (Bacillus cereus, Listeria monocytogenes, Micrococcus luteus, Staphylococcus aureus, Escherichia coli and Salmone...
34 CitationsSource
#1Isha JainH-Index: 3
#2Pankaj JainH-Index: 3
Last. Nidhi GuptaH-Index: 10
view all 6 authors...
The aim of the study was to comparatively evaluate the antibacterial activity of six Indian plant extracts and 0.2% chlorhexidine against clinical strains of Streptococcus mutans, which were isolated from the plaque samples of 45 pediatric patients. Six plant extracts were prepared in three different forms, namely aqueous extracts, organic solvent-based extracts and crude (raw) extracts. The antimicrobial sensitivity testing was done by agar well diffusion method. Antimicrobial activity of the e...
8 CitationsSource
#1Lisa Dei Cas (University of Milan)H-Index: 1
#2Francesca Pugni (University of Milan)H-Index: 1
Last. Gelsomina Fico (University of Milan)H-Index: 19
view all 3 authors...
Abstract Ethnopharmacological relevance In the past Alpine populations were isolated from comforts of industrial and technological development present in large cities and, therefore, they were obliged to find in nature a source of sustenance and care. Traditional use of plant is a wealth of local knowledge that is likely to be lost. This work, carried out during 2012, aims to collect, analyze and process information on the species used for medicinal, veterinary, cosmetic, domestic, ritual and re...
11 CitationsSource
view all 5 authors...
Objective: This study was subjected to analyze the technique for the determination of quercetin, a flavonoid in onion (Allium cepa L.) from three different cultivars of bulb onion (O1, O2, and O3) which were extracted with petroleum ether, chloroform, methanol, and water. Furthermore, this study was aimed to determine the antimicrobial activity of four solvent extracts of three onion cultivars against 10 microbial type culture collection (MTCC) bacterial pathogens. Methods: Quercetin in onion wa...
Medicinal plants such as Garlic and Onion (Allium sativum and Allium cepa) respectively, can be described as those plants in which one or more of its organs contain substances that can be used for chemotherapeutic purposes or precursors for the synthesis of useful drug. The use of plants in treating ailments has been in practice since a long time ago. The present study aimed to determine the antimicrobial activity of both aqueous and oil extracts of garlic and onion singly and mixed in vitro. An...
1 Citations
Background: Medicinal plants Garlic and Onion(Allium sativumand Alliumcepa)respectively,can be described as those plants in which one or more of its organs contain substances that can be used for chemotherapeutic purposes or precursors for the synthesis of useful drug.The use of plants in treating ailments has been in practice since a long time ago. Aims: The study aims at determining the antibacterial activity of aquatic garlic,onion and garlic-onion combination extract,then garlic oil,onion oi...