A method to differentiate between thyroglobulin derived from normal thyroid tissue and from thyroid carcinoma based on analysis of reactivity to lectins.
Abstract
The composition of sugar chains on thyroglobulin (Tg) produced in thyroid carcinoma cells (C-Tg) is different from Tg produced in normal thyroid tissues (N-Tg). In this study, we designed a new method for detecting Tg derived from thyroid carcinoma based on the differences between C-Tg and N-Tg in the reactivity with lectins.Thyroglobulin preparations obtained from various thyroid tissues were incubated with lectins, and the amount of...
Paper Details
Title
A method to differentiate between thyroglobulin derived from normal thyroid tissue and from thyroid carcinoma based on analysis of reactivity to lectins.
Published Date
Aug 1, 1998
Journal
Volume
122
Issue
8
Pages
715 - 20
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History