Original paper
Novel RET mutations in macedonian patients with medullary thyroid carcinoma: genotype-phenotype correlations.
Abstract
Medullary thyroid carcinomas (MTCs) are rare neoplasms comprising 2-10% of all thyroid malignnancies. More than 75% are sporadic tumors and the remainder is familial and MEN2 related. Both sporadic and syndromic MTCs frequently show mutations in the RET proto-oncogene. It has been noted that some MTC cases present an indolent, and some an aggressive clinical course. Ki-67 expression is generally low, with documented exceptions, whereas high...
Paper Details
Title
Novel RET mutations in macedonian patients with medullary thyroid carcinoma: genotype-phenotype correlations.
Published Date
Jan 1, 2015
Journal
Volume
36
Issue
1
Pages
93 - 107
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Notes
History