Abstract 933: Circulating biomarkers of B vitamins in relation to lung cancer risk in the Lung Cancer Cohort Consortium

Background - B vitamins and factors related to one-carbon metabolism help to maintain DNA and regulate gene expression. Some epidemiological data suggest that factors related to the one-carbon metabolism are important in the pathogenesis of several cancers, including lung cancer. Methods - Within the NCI Cohort Consortium, we designed a prospective case-control study including a total of 5,546 case-control pairs nested within 20 prospective...