Original paper
Dose-dependent model of caffeine effects on human vigilance during total sleep deprivation
Abstract
Caffeine is the most widely consumed stimulant to counter sleep-loss effects. While the pharmacokinetics of caffeine in the body is well-understood, its alertness-restoring effects are still not well characterized. In fact, mathematical models capable of predicting the effects of varying doses of caffeine on objective measures of vigilance are not available. In this paper, we describe a phenomenological model of the dose-dependent effects of...
Paper Details
Title
Dose-dependent model of caffeine effects on human vigilance during total sleep deprivation
Published Date
Oct 1, 2014
Volume
358
Pages
11 - 24
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