Original paper

Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation

Volume: 30, Issue: 6, Pages: 1382 - 1396
Published: Mar 1, 2010
Abstract
Cellular and biochemical studies support a role for all five human RecQ helicases in DNA replication; however, their specific functions during this process are unclear. Here we investigate the in vivo association of the five human RecQ helicases with three well-characterized human replication origins. We show that only RECQ1 (also called RECQL or RECQL1) and RECQ4 (also called RECQL4) associate with replication origins in a cell cycle-regulated...
Paper Details
Title
Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation
Published Date
Mar 1, 2010
Volume
30
Issue
6
Pages
1382 - 1396
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