Original paper
Differential analysis of gene regulation at transcript resolution with RNA-seq
Abstract
Differential analysis of gene and transcript expression using high-throughput RNA sequencing (RNA-seq) is complicated by several sources of measurement variability and poses numerous statistical challenges. We present Cuffdiff 2, an algorithm that estimates expression at transcript-level resolution and controls for variability evident across replicate libraries. Cuffdiff 2 robustly identifies differentially expressed transcripts and genes and...
Paper Details
Title
Differential analysis of gene regulation at transcript resolution with RNA-seq
Published Date
Dec 9, 2012
Journal
Volume
31
Issue
1
Pages
46 - 53
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Notes
History