Galectin 1 Modulates Plasma Cell Homeostasis and Regulates the Humoral Immune Response
Abstract
Galectin-1 (GAL1) is an S-type lectin with multiple functions, including the control of B cell homeostasis. GAL1 expression was reported to be under the control of the plasma cell master regulator BLIMP-1. GAL1 was detected at the protein level in LPS-stimulated B cells and was shown to promote Ig secretion in vitro. However, the pattern of GAL1 expression and function of GAL1 in B cells in vivo are still unclear. In this study, we show that,...
Paper Details
Title
Galectin 1 Modulates Plasma Cell Homeostasis and Regulates the Humoral Immune Response
Published Date
Jun 1, 2013
Journal
Volume
190
Issue
11
Pages
5526 - 5533
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