trans Palmitoleic acid arises endogenously from dietary vaccenic acid

trans Palmitoleic acid (t-16:1n–7, or 16:1t9 in the δ nomenclature usually applied to trans fatty acids and used herein) arouses great scientific interest because it has been suggested to serve as a biomarker for lower risks of type 2 diabetes and coronary artery disease. Although 16:1t9 has been assumed to derive from dietary sources, we examined the hypothesis that 16:1t9 might also be endogenously produced from its metabolic precursor...