Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
Abstract
A BLUEPRINT of immune cell development To determine the epigenetic mechanisms that direct blood cells to develop into the many components of our immune system, the BLUEPRINT consortium examined the regulation of DNA and RNA transcription to dissect the molecular traits that govern blood cell differentiation. By inducing immune responses, Saeed et al. document the epigenetic changes in the genome that underlie immune cell differentiation. Cheng...
Paper Details
Title
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
Published Date
Sep 26, 2014
Journal
Volume
345
Issue
6204
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Notes
History