Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

The genetic cause of intellectual disability in most patients is unclear because of the absence of morphological clues, information about the position of such genes, and suitable screening methods. Our aim was to identify de-novo variants in individuals with sporadic non-syndromic intellectual disability.In this study, we enrolled children with intellectual disability and their parents from ten centres in Germany and Switzerland. We compared...