Obesity and the Metabolic Syndrome in Children and Adolescents

The prevalence and magnitude of childhood obesity are increasing dramatically. We examined the effect of varying degrees of obesity on the prevalence of the metabolic syndrome and its relation to insulin resistance and to C-reactive protein and adiponectin levels in a large, multiethnic, multiracial cohort of children and adolescents.We administered a standard glucose-tolerance test to 439 obese, 31 overweight, and 20 nonobese children and...