BOLD responses to different temporal frequency stimuli in the lateral geniculate nucleus and visual cortex: Insights into the neural basis of fMRI

The neural basis of the blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) remains largely unknown after decades of research. To investigate this issue, the unique property of the temporal frequency tuning that could separate neural input and output in the primary visual cortex was used as a model. During moving grating stimuli of 1, 2, 10 and 20 Hz temporal frequencies, we measured 9.4-T BOLD fMRI responses...