Original paper
Longitudinal attentional engagement rescues mice from age-related cognitive declines and cognitive inflexibility
Abstract
Learning, attentional, and perseverative deficits are characteristic of cognitive aging. In this study, genetically diverse CD-1 mice underwent longitudinal training in a task asserted to tax working memory capacity and its dependence on selective attention. Beginning at 3 mo of age, animals were trained for 12 d to perform in a dual radial-arm maze task that required the mice to remember and operate on two sets of overlapping guidance (spatial)...
Paper Details
Title
Longitudinal attentional engagement rescues mice from age-related cognitive declines and cognitive inflexibility
Published Date
Apr 26, 2011
Journal
Volume
18
Issue
5
Pages
345 - 356
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Notes
History