The Arc of synaptic memory
Abstract
The immediate early gene Arc is emerging as a versatile, finely tuned system capable of coupling changes in neuronal activity patterns to synaptic plasticity, thereby optimizing information storage in the nervous system. Here, we attempt to overview the Arc system spanning from transcriptional regulation of the Arc gene, to dendritic transport, metabolism, and translation of Arc mRNA, to post-translational modification, localization, and...
Paper Details
Title
The Arc of synaptic memory
Published Date
Aug 19, 2009
Journal
Volume
200
Issue
2
Pages
125 - 140
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History