Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma
Abstract
The Breast Cancer Resistance Protein (BCRP/ABCG2) is one member of ABC transporters proteins super family responsible of drug resistance. Since data on ABCG2 expression in liver malignances are scanty, here we report the expression of ABCG2 in adult human hepatocellular carcinoma (HCC) in both in vivo and in vitro models with different degree of malignancy.In cell lines derived from human hepatocellular carcinoma, ABCG2 gene expression was...
Paper Details
Title
Gene and functional up-regulation of the BCRP/ABCG2 transporter in hepatocellular carcinoma
Published Date
Nov 15, 2012
Journal
Volume
12
Issue
1
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