Enhanced production of an extracellular protease from Beauveria bassiana by optimization of cultivation processes

Statistics-based experimental design, response surface methodology was employed to investigate the effect of medium components on the production of extracellular protease from Beauveria bassiana A1. The optimum medium composition for protease production was found to be (in %, w/v): 0.72 shrimp shell powder, 0.60 soy powder, 0.19 sucrose and 0.68 yeast extract. This medium was projected to produce, theoretically, 281.14 U/ml. By using this...