The impact of melancholia versus non-melancholia on resting-state, EEG alpha asymmetry: Electrophysiological evidence for depression heterogeneity

While depression has been associated with relatively greater right than left frontal cortical activity – a neurophysiological marker reflecting greater activation of the withdrawal system – contradictory findings have been reported. It was hypothesised that melancholia would be associated with relative right frontal activation, in comparison to non-melancholia and controls. We collected 2-min of resting-state, eyes closed,...