Cas9 as a versatile tool for engineering biology
Abstract
RNA-guided Cas9 nucleases derived from clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have dramatically transformed our ability to edit the genomes of diverse organisms. We believe tools and techniques based on Cas9, a single unifying factor capable of colocalizing RNA, DNA and protein, will grant unprecedented control over cellular organization, regulation and behavior. Here we describe the Cas9 targeting...
Paper Details
Title
Cas9 as a versatile tool for engineering biology
Published Date
Sep 27, 2013
Journal
Volume
10
Issue
10
Pages
957 - 963
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