Original paper
Early Mucosal Healing With Infliximab Is Associated With Improved Long-term Clinical Outcomes in Ulcerative Colitis
Abstract
Background & AimsIn the Active Ulcerative Colitis Trial (ACT)-1 and ACT-2, patients with ulcerative colitis treated with infliximab were more likely than those given placebo to have a clinical response, undergo remission, and have mucosal healing. We investigated the association between early improvement (based on endoscopy) and subsequent clinical outcome.MethodsPatients underwent endoscopic evaluations at weeks 0, 8, 30, and 54 (ACT-1 only),...
Paper Details
Title
Early Mucosal Healing With Infliximab Is Associated With Improved Long-term Clinical Outcomes in Ulcerative Colitis
Published Date
Oct 1, 2011
Journal
Volume
141
Issue
4
Pages
1194 - 1201
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Notes
History