Foxe view of lens development and disease
Abstract
The recent identification of a mutation in Foxe3 that causes congenital primary aphakia in humans marks an important milestone. Congenital primary aphakia is a rare developmental disease in which the lens does not form. Previously, Foxe3 had been shown to play a crucial role in vertebrate lens formation and this gene is one of the earliest integrators of several signaling pathways that cooperate to form a lens. In this review, we highlight...
Paper Details
Title
Foxe view of lens development and disease
Published Date
Apr 15, 2007
Journal
Volume
134
Issue
8
Pages
1455 - 1463
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