Original paper
Discovery of novel antiviral agents directed against the influenza A virus nucleoprotein using photo-cross-linked chemical arrays
Volume: 394, Issue: 3, Pages: 721 - 727
Published: Apr 1, 2010
Abstract
The nucleoprotein (NP) of the influenza virus is expressed in the early stage of infection and plays important roles in numerous steps of viral replication. NP is relatively well conserved compared with viral surface spike proteins. This study experimentally demonstrates that NP is a novel target for the development of new antiviral drugs against the influenza virus. First, artificial analogs of mycalamide A in a chemical array bound...
Paper Details
Title
Discovery of novel antiviral agents directed against the influenza A virus nucleoprotein using photo-cross-linked chemical arrays
Published Date
Apr 1, 2010
Volume
394
Issue
3
Pages
721 - 727
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Notes
History