Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation
Abstract
Tissue factor (TF) is expressed on nonvascular cells and cells within the vessel wall and circulates in blood associated with microparticles. Although blood-borne TF accumulates into the developing thrombus during thrombus formation, the contribution of blood-borne TF and vessel wall TF to thrombin generation in vivo following vessel injury is unknown. To determine the source and role of blood-borne microparticle TF, we studied arterial thrombus...
Paper Details
Title
Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation
Published Date
Nov 15, 2004
Journal
Volume
104
Issue
10
Pages
3190 - 3197
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