Konjac glucomannan, a promising polysaccharide for OCDDS

Oral colon targeting drug delivery system (OCDDS) is a highly effective formulation for drugs absorbed by colon, or to treat colonic diseases specifically. To obtain colon targeting, many pharmaceutical approaches have been studied, among which, taking advantage of specific degradation of excipients by colon enzymes is one of the most promising strategies. With properties of specific colon β-mannanase degradation, biocompatibility, gel-forming,...