Original paper
Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers
Abstract
Although threshold levels for hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) titers have recently been proposed to guide therapy for chronic hepatitis B (CHB), their relationship to circulating hepatitis B virus (HBV) DNA and intrahepatic HBV replicative intermediates, and the significance of emerging viral variants, remains unclear. We therefore tested the hypothesis that HBsAg and HBeAg titers may vary independently of...
Figures & Tables
Fig. 1. (A) Population distribution of HBsAg titer (n ¼ 149), comparing patients...
Fig. 2. (A) Correlation of serum HBsAg titer and HBV DNA level, according to HBe...
Fig. 3. In patients with HBeAg-negative CHB, hepatocyte HBsAg expression, as mea...
Fig. 4. Population distribution of HBeAg titer (n ¼ 71), for (A) the overall coh...
Fig. 5. Diagram of the lifecycle of HBV, highlighting the separate intracellular...
Table 1. Baseline Patient Data
Table 2. Correlation Between HBsAg and HBeAg Titer and Serum and Intrahepatic HB...
Table 3. (A) Correlation Between HBsAg, HBeAg Titer, Serum/Intrahepatic HBV Repl...
Paper Details
Title
Serum hepatitis B surface antigen and hepatitis B e antigen titers: Disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers
Published Date
Feb 1, 2010
Journal
Volume
51
Issue
6
Pages
1933 - 1944
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