Review paper
Pharmacology and potential physiological significance of schistosome multidrug resistance transporters
Abstract
Schistosomes are the causative agents of schistosomiasis, a neglected tropical disease affecting hundreds of millions worldwide and a major global health burden. Current control of schistosomiasis depends largely on a single drug, praziquantel (PZQ). One potential physiological target for new antischistosomal drugs is the parasite's excretory system, which removes wastes and xenobiotics. Multidrug resistance (MDR) transporters that are members...
Paper Details
Title
Pharmacology and potential physiological significance of schistosome multidrug resistance transporters
Published Date
Sep 1, 2012
Journal
Volume
132
Issue
1
Pages
2 - 6
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