Original paper
Crystal Structure of an Anti-anti-idiotype Shows it to be Self-complementary
Abstract
The structure of the Fab fragment of the mouse anti-anti-idiotypic monoclonal antibody (mAb) GH1002 was solved by X-ray crystallography. mAb GH1002 was elicited with the syngeneic anti-idiotype mAb MK2-23 which mimics the determinant defined by anti-human high molecular weight-melanoma associated antigen (HMW-MAA) mAb 763.74. The Fab fragments of mAb GH1002 exist in the crystal as dimers related by crystallographic 2-fold axes. The interface...
Paper Details
Title
Crystal Structure of an Anti-anti-idiotype Shows it to be Self-complementary
Published Date
Feb 1, 1996
Journal
Volume
255
Issue
4
Pages
617 - 627
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Notes
History