Review paper
Multi-Arm Clinical Trials of New Agents: Some Design Considerations
Abstract
A major challenge in the development of anticancer therapies is the considerable time and resources needed for conducting randomized clinical trials (RCT). There is a need for more efficient RCT designs that accelerate development, minimize costs, and make trials more appealing to patients. We review the statistical and logistical characteristics of multi-arm designs that compare several experimental treatments to a common control arm. In...
Paper Details
Title
Multi-Arm Clinical Trials of New Agents: Some Design Considerations
Published Date
Jul 15, 2008
Journal
Volume
14
Issue
14
Pages
4368 - 4371
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