Review paper
Qualified kidney biomarkers and their potential significance in drug safety evaluation and prediction
Abstract
The kidney is one of the major organs drug toxicity may target. Some renal safety biomarkers have been proposed to measure kidney injury and function accordingly. Despite the widespread use for diagnosis and monitoring of renal injury and function for decades, serum creatinine and blood urea nitrogen are nonspecific biomarkers with insensitive and delayed response in the clinical setting. There is an urgent need to identify and qualify novel...
Paper Details
Title
Qualified kidney biomarkers and their potential significance in drug safety evaluation and prediction
Published Date
Jan 1, 2013
Journal
Volume
137
Issue
1
Pages
100 - 107
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