Label-Free Plasmonic Detection of Biomolecular Binding by a Single Gold Nanorod
Abstract
We report the use of individual gold nanorods as plasmonic transducers to detect the binding of streptavidin to individual biotin-conjugated nanorods in real time on a surface. Label-free detection at the single-nanorod level was performed by tracking the wavelength shift of the nanorod-localized surface plasmon resonant scattering spectrum using a dark-field microspectroscopy system. The lowest streptavidin concentration that was experimentally...
Paper Details
Title
Label-Free Plasmonic Detection of Biomolecular Binding by a Single Gold Nanorod
Published Date
Jan 16, 2008
Journal
Volume
80
Issue
4
Pages
984 - 989
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