Positive Correlation of Oct4 and ABCG2 to Chemotherapeutic Resistance in CD90+CD133+Liver Cancer Stem Cells
Abstract
Liver cancer is one of the most common tumors worldwide and drug resistance is a major obstacle to successful therapy. The growing data show that cancer stem cells (CSCs), a rare subpopulation of cancer cells, might be an important mechanism of drug resistance. To explore the self-renewal ability and chemotherapy resistance in liver CSCs, we enriched CD90+CD133+ hepatocellular carcinoma (HCC) CSCs using sphere formation, which was accomplished...
Paper Details
Title
Positive Correlation of Oct4 and ABCG2 to Chemotherapeutic Resistance in CD90+CD133+Liver Cancer Stem Cells
Published Date
Apr 1, 2013
Journal
Volume
15
Issue
2
Pages
143 - 150
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