Visceral fat and metabolic inflammation: the portal theory revisited
Abstract
Abdominal (central) obesity strongly correlates with (hepatic) insulin resistance and type 2 diabetes. Among several hypotheses that have been formulated, the 'portal theory' proposes that the liver is directly exposed to increasing amounts of free fatty acids and pro-inflammatory factors released from visceral fat into the portal vein of obese patients, promoting the development of hepatic insulin resistance and liver steatosis. Thus, visceral...
Paper Details
Title
Visceral fat and metabolic inflammation: the portal theory revisited
Published Date
Oct 29, 2012
Journal
Volume
13
Issue
S2
Pages
30 - 39
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