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Daniel Konrad
Boston Children's Hospital
80Publications
27H-index
2,929Citations
Publications 80
Newest
#1Timothy S. Odermatt (UZH: University of Zurich)
#2Mara Dedual (UZH: University of Zurich)
Last.Daniel Konrad (UZH: University of Zurich)H-Index: 27
view all 5 authors...
Repetitive physical activity is a well-established intervention to reduce obesity and to prevent weight regain. Besides increased energy expenditure, reduced caloric intake may contribute to exercise-induced weight loss in obesity. Using adipocyte-specific glycoprotein 130 knockout (gp130Δadipo) mice, we recently unravelled that obesity-induced interleukin-6 (IL-6) signalling in adipose tissue contributes to circulating levels of the two anorectic hormones leptin and insulin. Herein, we aimed to...
#1Tenagne D. Challa (Boston Children's Hospital)H-Index: 2
#2Stephan Wueest (Boston Children's Hospital)H-Index: 15
Last.Daniel Konrad (UZH: University of Zurich)H-Index: 27
view all 9 authors...
#1Gilbert KochH-Index: 5
#2Verena GottaH-Index: 5
Last.F Bachmann (University of Konstanz)
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Background Thyroid hormones are essential for normal growth and puberty in children and adolescents. Graves’ disease (GD) is a rare autoimmune disorder associated with thyroid hormone over-production and occurs in 0.5–2:100’000 children (mostly females) in Europe. In contrast to adults, first line treatment of GD is long-term antithyroid drug (ATD) therapy, and radioiodine ablation is usually being reserved for patients after puberty. However, treatment of acquired hyperthyroidism with ATD is di...
#1Grit Sommer (University of Bern)H-Index: 5
#2Daniel Konrad (Boston Children's Hospital)H-Index: 27
Last.Urs ZumstegH-Index: 12
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Wie werden heute Kinder mit unklarem Geschlecht in der Schweiz betreut? Diese und ahnliche Fragen beschaftigen nicht nur Spezialist(inn)en und Betroffene, sondern auch die Offentlichkeit. Die Nationale Ethikkommission hat 2012 Empfehlungen zum Umgang mit Menschen mit Varianten der Geschlechtsentwicklung erarbeitet.
#1Grit Sommer (University of Bern)H-Index: 5
#2Daniel Konrad (Boston Children's Hospital)H-Index: 27
Last.Urs ZumstegH-Index: 12
view all 10 authors...
#1Gerald GrandlH-Index: 4
#2Leon G. StraubH-Index: 5
Last.Christian WolfrumH-Index: 29
view all 7 authors...
KEY POINTS A ketogenic diet is known to lead to weight loss and is considered metabolically healthy; however there are conflicting reports on its effect on hepatic insulin sensitivity. KD fed animals appear metabolically healthy in the fasted state after 3 days of dietary challenge, whereas obesogenic high-fat diet (HFD) fed animals show elevated insulin levels. A glucose challenge reveals that both KD and HFD fed animals are glucose intolerant. Glucose intolerance correlates with increased lipi...
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