Epidermal growth factor receptor‐targeted liposome with cisplatin enhances radiotherapeutic efficacy without nephrotoxicity

Radiotherapy is one of the major modalities for non-small cell lung cancer (NSCLC), but its efficacy is often compromised by cellular resistance caused by various mechanisms including the overexpression of epidermal growth factor receptor (EGFR). Although cisplatin (CDDP) has been well characterized as an effective radiosensitizer, its clinical application is limited by its severe nephrotoxic effects. In our current study, we developed a...