Hiding the Elephant in the Room with Experimental Neutrons

Volume: 119, Issue: 2, Pages: 234 - 235
Published: Jul 1, 2020
Abstract
The unfolding and proteolysis of proteins in the cell is an essential homeostatic process. This labor is performed by the proteasome: a large ∼2 MDa (26S) assembly of AAA+ proteins working in concert. Across prokaryotes, eukaryotes, and archaea, this ring-like particle features a central cavity in which ATP-driven proteolysis occurs, in collaboration with partner proteins that mediate unfolding and substrate entry. X-ray crystallography and...
Paper Details
Title
Hiding the Elephant in the Room with Experimental Neutrons
Published Date
Jul 1, 2020
Volume
119
Issue
2
Pages
234 - 235
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