Progressive and accelerated weight and body fat loss in Parkinson's disease: A three-year prospective longitudinal study

Introduction Although weight loss is common in Parkinson's disease (PD), longitudinal studies assessing weight and body composition changes are limited. Methods In this three-year longitudinal study, 125 subjects (77 PD patients and 48 spousal/sibling controls) underwent clinical, biochemical and body composition assessments using dual-energy X-ray absorptiometry. Results Patients were older than controls (65.6 ± 8.9 vs. 62.6 ± 7.1, P = 0.049),...