Macrophages fine-tune pupil shape during development
Abstract
Tissue macrophages, which are ubiquitously present innate immune cells, play versatile roles in development and organogenesis. During development, macrophages prune transient or unnecessary synapses in neuronal development, and prune blood vessels in vascular development, facilitating appropriate tissue remodeling. In the present study, we identified that macrophages contributed to the development of pupillary morphology. Csf1op/op mutant mice,...
Paper Details
Title
Macrophages fine-tune pupil shape during development
Published Date
Aug 1, 2020
Journal
Volume
464
Issue
2
Pages
137 - 144
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History