Original paper
DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system
Abstract
Background CRISPR-Cas systems, which provide adaptive immunity against foreign nucleic acids in prokaryotes, can serve as useful molecular tools for multiple applications in genome engineering. Diverse CRISPR-Cas systems originating from distinct prokaryotes function through a common mechanism involving the assembly of small crRNA molecules and Cas proteins into a ribonucleoprotein (RNP) effector complex, and formation of an R-loop structure...
Paper Details
Title
DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system
Published Date
Jun 15, 2020
Journal
Volume
18
Issue
1
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Notes
History