FARFAR2: Improved De Novo Rosetta Prediction of Complex Global RNA Folds
Abstract
Predicting RNA three-dimensional structures from sequence could accelerate understanding of the growing number of RNA molecules being discovered across biology. Rosetta's Fragment Assembly of RNA with Full-Atom Refinement (FARFAR) has shown promise in community-wide blind RNA-Puzzle trials, but lack of a systematic and automated benchmark has left unclear what limits FARFAR performance. Here, we benchmark FARFAR2, an algorithm integrating...
Paper Details
Title
FARFAR2: Improved De Novo Rosetta Prediction of Complex Global RNA Folds
Published Date
Aug 1, 2020
Journal
Volume
28
Issue
8
Pages
963 - 976.e6
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