Original paper
Decellularized hepatic extracellular matrix hydrogel attenuates hepatic stellate cell activation and liver fibrosis
Abstract
Liver fibrosis results from excessive accumulation of extracellular matrix (ECM) proteins that distort the hepatic architecture. Progression of liver fibrosis results in cirrhosis and liver failure, and often, liver transplantation is required. The decellularized liver tissue contains different components that mimic the natural hepatic environment. We hypothesized that a decellularized liver hydrogel can be used to replace the necrotic...
Paper Details
Title
Decellularized hepatic extracellular matrix hydrogel attenuates hepatic stellate cell activation and liver fibrosis
Published Date
Nov 1, 2020
Volume
116
Pages
111160 - 111160
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