Original paper
Bayesian reassessment of the epigenetic architecture of complex traits
Abstract
Linking epigenetic marks to clinical outcomes improves insight into molecular processes, disease prediction, and therapeutic target identification. Here, a statistical approach is presented to infer the epigenetic architecture of complex disease, determine the variation captured by epigenetic effects, and estimate phenotype-epigenetic probe associations jointly. Implicitly adjusting for probe correlations, data structure (cell-count or...
Paper Details
Title
Bayesian reassessment of the epigenetic architecture of complex traits
Published Date
Jun 8, 2020
Journal
Volume
11
Issue
1
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History