Retinoids in the visual cycle: role of the retinal G protein-coupled receptor
Abstract
Driven by the energy of a photon, the visual pigments in rod and cone photoreceptor cells isomerize 11-cis-retinal to the all-trans configuration. This photochemical reaction initiates the signal transduction pathway that eventually leads to the transmission of a visual signal to the brain and leaves the opsins insensitive to further light stimulation. For the eye to restore light sensitivity, opsins require recharging with 11-cis-retinal. This...
Paper Details
Title
Retinoids in the visual cycle: role of the retinal G protein-coupled receptor
Published Date
Jan 1, 2021
Journal
Volume
62
Pages
100040 - 100040
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