Senescent Cells in Cancer Therapy: Friends or Foes?
Abstract
Cellular senescence is a common outcome of various anticancer interventions.Senescence-associated secretory phenotypes (SASPs) have pro-tumorigenic functions.Evidence exists of increased cellular senescence in patients treated for various types of cancer.Therapy-induced senescence can cause cancer metastasis and relapse and several adverse reactions to cancer treatments.Pharmacological interference with detrimental senescence might be considered...
Paper Details
Title
Senescent Cells in Cancer Therapy: Friends or Foes?
Published Date
Oct 1, 2020
Journal
Volume
6
Issue
10
Pages
838 - 857
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Notes
History