Assessment of a causal relationship between body mass index and atopic dermatitis

Atopic dermatitis (AD) is an itchy, inflammatory skin condition associated with multiple comorbidities. Observational epidemiology suggests an increased prevalence of obesity in patients with AD, but (1) whether there is a causal effect and (2) whether obesity leads to AD or vice versa remain unclear. Genetic predisposition to obesity has been shown to promote psoriasis,1Budu-Aggrey A. Brumpton B. Tyrrell J. Watkins S. Modalsli E.H....